Michigan ANG units are trained and equipped by the Air Force and are operationally gained by a Major Command of the USAF if federalized.

State missions include disaster relief in times of earthquakes, hurricanes, floods and forest fires, search and rescue, protection of vital public services, and support to civil defense.

The 107th Observation Squadron was ordered into active service on 15 October 1940 as part of the buildup of the Army Air Corps prior to the United States entry into World War II.

The 67th Group did anti-submarine patrolling off the East Coast of the US from mid-December 1941 to March 1942, when it returned to Louisiana for training in fighter aircraft.

The 67th Group was sent to Membury, England, in August 1942 and flew the Spitfire Mk V and Tiger Moths for a year until equipped with the F-6A Mustang.

Before the Normandy landings in June 1944, pilots of the Michigan National Guard's 107th Tactical Reconnaissance Squadron were flying photographic missions in preparation for D-Day.

The squadron's pilots flew 384 missions to perform the dangerous task of photographically mapping the French coast before D-Day.

On 24 May 1946, the United States Army Air Forces, in response to dramatic postwar military budget cuts imposed by President Harry S. Truman, allocated inactive unit designations to the National Guard Bureau for the formation of an Air Force National Guard.

Initial priority was given to the organization of the State Headquarters, the 46th Infantry Division, and Air National Guard units.

26 Michigan Army and Air National Guard units were called to active military service during the Korean War.

[9] When tensions began to reach the breaking point with Kosovo refugees being forced out of their homes in Yugoslavia, In 1997 the 110th Fighter Wing took part in Operation Deny Flight in 1997.

In 1996, air crew members and maintainers from the airlift element of the 127th Fighter Wing deployed to Germany over a period of two months to fly support shuttle missions into Bosnia as part of Operation Joint Endeavor.

The 171st Airlift Squadron of the 127th Wing is the last Air National Guard unit to perform missions from Howard Air Force Base in Panama and members of the 1775th and 46th Military Police Companies provided law enforcement services and security as Fort Clayton, Panama was closed down.