Other adversaries have included Emil Eagle, Eli Squinch, Sylvester Shyster, the team of Dangerous Dan McBoo and Idjit the Midget, and the Phantom Blot.

[1] In the mid 1930s original Mickey comic book stories were being produced in Italy and the United Kingdom for local consumption.

[6] In the words of historian Michael Barrier: "Reprinted newspaper comics were never more than a minor part of its lineup until the very last issue, dated September 1940, when they suddenly took up half the pages".

The American Mickey Mouse title experienced changes in artists, publishers, length, cost, and printing quality over the years.

A unique experiment deviating from the norm occurred in 1966: Inspired by the James Bond spy mania of the period for three issues (#107–109) the comic was titled Mickey Mouse, Super Secret Agent with stories of Mickey and Goofy becoming international spies and interacting with human characters in realistic settings.

[9] While Mickey and Goofy were drawn in the usual "cartoony" style by Paul Murry, the other characters and backgrounds were done by Dan Spiegle in a realistic manner.

Although the circulation of Mickey Mouse had declined for years, especially compared to Uncle Scrooge, in 1987 Gladstone said it had become their top selling title.

[13] Even so, in late 1987 Gladstone announced they were cutting all their publications back to eight issues per year (because comics sell less well in fall and winter).

Mickey Mouse ceased publication in 1990, with issue #256, when Gladstone lost their license to publish the Disney characters.

The story has been reprinted in Walt Disney's Mickey Mouse: "Trapped on Treasure Island" (1932–33 dailies; 2011) ISBN 978-1-60699-495-5.

Studios assumed the license for Disney's stable of comic book characters and resumed publication of both Mickey Mouse and Friends and WDC&S under their Boom!

Studios' Mickey Mouse and Friends contains full-issue, multi-part modern stories originally created in Europe and translated to English.

Studios titles changed to Kaboom!, but by October of that year all Disney comics, including Mickey Mouse, ceased publication.

IDW also relaunched Donald Duck, Uncle Scrooge and Walt Disney's Comics and Stories at the time.

IDW issues of Mickey Mouse, generally containing 35–40 pages of comics apiece, are slightly longer than the earlier Boom and Gemstone issues, and tend to feature extended-length adventure stories from two of the best-known Italian Mickey creators, Romano Scarpa and Andrea "Casty" Castellan.