It is a nocturnal, terrestrial and fossorial snake, which digs loose soil or litter, has been one of the main accident-causing corals in Southeast South America, although it is not relatively aggressive towards humans, it has Oviparous reproduction, although eggs / clutch has not been reported.

[1][2] It mainly lives in humid forests, tropical and subtropical deciduous forests, savannas, sandy and rocky areas, in secondary vegetation such as pastures and agricultural land, close to marshes and streams, it inhabits lowlands, from sea level to an elevation of 700 m.[4] It feeds on lizards and other snakes (including blind snakes).

[4] Like all elapids in Brazil, Micrurus frontalis has post-synaptic neurotoxins (except for Micrurus corallinus) that bind to terminal motor acetylcholine receptors, the toxin is composed of low molecular weight polypeptides, which are rapidly absorbed by the body after inoculation and symptoms can appear in minutes, the toxin acts peripherally, blocking neuromuscular transmission.

Muscle paralysis is a consequence of the action of the toxin with the neurotransmitter by the nicotinic receptor on the end plate.

At the site of the bite, edema and paresthesias occur, the initial systemic symptoms of most coral accidents, include eyelid ptosis and diplopia, which are followed by facial muscle paralysis, visual impairment, anisocoria, dysarthria, dysphagia, salivation and generalized loss of muscle strength, in severe cases, life-threatening respiratory arrest occurs, with patients requiring artificial ventilation.