Mid-Missouri

Mid-Missouri is a loosely-defined region comprising the central area of the U.S. state of Missouri.

[2] Counties that are usually considered to be in Mid-Missouri are Audrain, Boone, Callaway, Camden, Chariton, Cole, Cooper, Gasconade, Howard, Macon, Miller, Moniteau, Montgomery, Morgan, Osage, Pettis, Randolph, and Saline.

Counties that are sometimes considered to be in the region are Adair, Benton, Laclede, Maries, Phelps, Pulaski, and Warren.

Interstate Highways 70 (concurrent with U.S. 40) and 44 both pass through the region and intersect with each other in St. Louis.

Columbia Regional Airport (COU) is the only commercial airport in Mid-Missouri and is served by American Eagle with non-stop service to either Dallas/Fort Worth Chicago-O'Hare or Denver International as well as providing general aviation services.