Further inland, annual rainfall decreases to less than 250 millimetres (10 in), and here the economy is dominated by mining of iron ore, gold, nickel and other mineral resources.

Western Rock Lobster netted almost $234.5 million in revenue for WA in the 2012–13 financial year, making it Australia's most valuable single-species wild capture fishery.

The Blueprint proposes strategies against five priority pillars to drive or reduce barriers to, regional growth and development in the Mid West.

[6] Due to its relative isolation from radio-frequency interference, the Mid West region was selected to host one of two primary radiotelescope locations of the Square Kilometre Array (SKA) project.

High-capacity optical fibre cables connect the SKA telescope to the MRO support facility in Geraldton and to the Pawsley Supercomputing Centre in Perth, Western Australia.

The local government areas in the Mid West region are Carnamah, Chapman Valley, Coorow, Cue, Greater Geraldton, Irwin, Meekatharra, Mingenew, Morawa, Mount Magnet, Murchison, Northampton, Perenjori, Sandstone, Three Springs and Yalgoo.