From northeast to southwest: At the time of his death in 1807, 46-year-old Commodore Edward Preble was living on Middle Street.

[10] The Samuel Freeman House, built in the late 18th century, formerly stood on Middle Street.

[13]The 240-room, six-story Falmouth Hotel stood at 212 Middle Street between 1868 and 1963, when it was torn down for being a fire hazard.

It was replaced by today's Canal Bank Plaza in 1971.

[14] Sanitary Meat Market (established in 1914) formerly occupied the southern corner of the Middle Street and India Street intersection.