Lady Anne House is a former almshouse, now a hotel, in York, in England.
The almshouse was founded by Ann Middleton, in 1659, on a site on Skeldergate, in the Bishophill area of York.
Known as Middleton's Hospital, it had 22 apartments around a small yard, housing twenty widows.
[1] In 1827, the hospital was demolished, and rebuilt further back from the street, as a two-storey brick structure.
In the centre of the front is a statue of a woman in Puritan dress, which is believed to survive from the original building.