Mignon O'Doherty (1890 – 1961) was an Australian actress who worked in British theatre, film and television.

O'Doherty was born in Brisbane, the daughter of Dr. Edward O’Doherty and Isabel Maud French.

She was the granddaughter of Young Irelander Dr. Kevin Izod O’Doherty and his wife, the Irish revolutionary poet Mary Eva Kelly.

She was also the granddaughter of General Sir George French, first commissioner of Canada’s Northwest Mounted Police.

O'Doherty was in the original cast of Agatha Christie's The Mousetrap, in which she played Mrs. Boyle, at the Ambassadors Theatre, London from 1952 to 1955.