His brother was Ángel Masié Ntutumu, first minister of the Interior of Francisco Macías Nguema.

In 1948 he joined the Colonial Guard of Spanish Guinea, which he left in 1950 to enter the commercial sector.

[2] After the independence of Equatorial Guinea from Francoist Spain, he served since October 1968 as President of the Provincial Council [es][4] and since July 1971 as civil governor of Río Muni.

[7][8] After the dismissal of Edmundo Bossio in 1974, Eyegue took office on March 2 of that year as acting Vice President of Equatorial Guinea.

[9][10] After the 1979 coup d'état led by Teodoro Obiang Nguema Mbasogo, Eyegue was tried alongside Macías and other defendants for crimes committed during the dictatorship.