Mihran is first mentioned during the Arab invasion of Persia, and is known to have commanded the left wing of the Sasanian army during the battle of al-Qādisiyyah.
[1] Mihran, along with Nakhiragan, Hormuzan and Piruz Khosrow, including the rest of the survivors, regrouped at Bavel (Babylon), where they tried to repel the Arab army, but were once again defeated.
After a brief stay at Veh-Ardashir,[3] they abandoned and destroyed the bridge on the east bank of the Tigris river.
Nakhiragan and Mihran then briefly stayed at Kutha, where they installed a certain dehqan named Shahriyar as the commander of the garrison of the place.
Mihran along with the rest of the survivors then fled to Khanaqin, but were at last killed by an Arab force which had pursued them.