Imai Hotaru (今井 蛍) Voiced by: Rie Kugimiya (anime), Miyuki Sawashiro (Gakuen Alice Drama CD--only released bundled with a copy of Hana to Yume magazine) Hotaru Imai is Mikan's 10-year-old best friend and possesses the Alice of invention, which enables her to invent anything that comes to life easily, making her the target of admiration among technical and engineering companies.
Although she frequently scolds and hits her best friend, she is actually deeply caring and treasures her dearly like a sister, preferring to show her love in a different, more quiet, manner.
Her relationship with her brother, Subaru, seems cool on the exterior as they often insult each other and compete in intelligence, but both recognise the fact that that is their way of being closer to each other through sibling rivalry and love.
As a final gesture of her affection for Mikan, Hotaru sacrifices her existence to save Natsume from dying, causing her and Subaru to be trapped in the time realm.
Hyūga Natsume (日向 棗) Voiced by: Romi Park Natsume Hyūga is the male protagonist in the series, possessing the Alice of fire, a powerful and uncontrollable Alice that runs in his family and will whittle away at his lifespan through overuse.
However, he starts to see her caring and optimistic personality, and falls in love with her, referring to her as his sun or light.
Due to his handsomeness and gentle and pleasant personality, which balance out that of Natsume, he is popular among his classmates, especially girls.
Tobita Yū (飛田 裕) Voiced by: Fuyuka Oura Yū Tobita is Class B's representative (thus known by the majority of the class as "Inchō" or "Inchou" however in the English translation of the manga he is known as "Prez") and possesses the Alice of illusion, allowing him to specialise in conducting hallucinations.
He is Hotaru's companion before Mikan arrives at Alice Academy and is known for his shy, gentle personality and studious behavior.
[2] He is very good friends with Mikan and was one of the first to actually treat her nicely upon her entering Class B. Shouda Sumire (正田 スミレ) Voiced by: Chiwa Saito Sumire Shouda is the self-proclaimed president of a fanclub idolizing Natsume and Ruka.
Sumire is initially jealous of Mikan receiving so much attention from Natsume and Ruka, but warms up to her later in the series.
As a farewell gift, the rest of the Special Ability class gave him their Alice stones, Mikan included.
She has the Doppelgänger Alice and is also a member of the Watching Over Ruka group, and it somehow appears that Kitsuneme and Yome have innocent crushes on her.
[8] When Tsubasa goes to save Mikan, he asks Misaki to be his girlfriend if he comes back alive, and she states that she thought they had already been going out.
In the anime, it is said that he has a crush on Megumi during the Special Ability's role-playing game at the Alice Festival.
She first appeared in episode 19 of the anime, where she was supposed to act as the prince but later was replaced by Mikan because of an incident where sticking gum/bomb was stuck on her hands, body, and foot.
Because of saving Hotaru from the school (chapter 98), Hayate cannot go back to the Dangerous Ability Class anymore.
She is in the Latent Ability Class and possesses the Alice to predict the future, though it first requires a comical dance to activate.
Subaru is normally cold and doesn't hesitate to throw insults at Hotaru, though he has a soft spot for Mikan.
Narumi・Eru・Anju (鳴海・L・杏樹) Voiced by: Akira Ishida Narumi L. Anju is Mikan's homeroom teacher, who often deals with Natsume when he gets in trouble or tries to break out of the academy.
Noda (野田) Voiced by: Mamoru Miyano Nodacchi is the moderator of the Special Ability Class.
The students, except for Mikan, and Yū, do not respect him and usually torment him, leaving him to run out of the room in fright and tears.
In the manga,[9] he accompanies Narumi in one of the trips made to persuade Ruka and Natsume to enter Gakuen Alice.
He entered in the academy at age 22 and became the moderating teacher of the Special Ability Class befriended a then 10-year-old Yuka when she was sad about being abandoned by her parents.
After betraying Kuonji and reconciling with Mikan, Persona leaves the academy, marries Nobara, and they have a daughter.
Years later, she returns to the academy to rescue Mikan and the two reconcile before she is killed by a bomb planted by Goshima at Kuonji's order.
He arrives in the academy to kidnap Natsume but this plan is ruined due to Mikan and Sumire's intervention.
When she accidentally destroyed their village, Natsume took the blame and was sent to the academy, and Aoi was held captive by Persona.
It figured prominently in the Z arc when it stowed away in Mikan's backpack and eventually ends up saving the day and sadly vanishes into the depths of a hole in the ground not to be seen again.
She occasionally appears in the anime dressed as a student sitting in the 3rd row, same as Hotaru, on the right side of the room.