[1][3] As a pitcher, Belfiore compiled a 0–2 record with a 10.45 earned run average (ERA), one save, and five strikeouts in seven games, one start.

During his sophomore season at Boston College, Belfiore batted .274 with 10 doubles, two home runs, and 26 RBIs as a position player.

[2][6] During the 2009 Major League Baseball draft, the Arizona Diamondbacks selected Belfiore with the 45th pick in the first round.

[11] Belfiore made his professional baseball debut in 2009 with the rookie-level Missoula Osprey of the Pioneer League.

[12] On the subject of pitching in professional baseball, Belfiore said, "In college I just threw fastballs and a slider and blew guys away...You have to use your changeup and understand hitters counts [at this level]".

At the start of the 2010 season, Belfiore was assigned to play with the South Bend Silver Hawks of the Class-A Midwest League.

On April 3, 2014, the Detroit Tigers claimed Belfiore off waivers and sent him to the Triple-A Toledo Mud Hens.

[16] He was released on August 15, 2015, to make room for Kyle Lobstein, who was sent to the Mud Hens on a rehab assignment.