In 2004 he completed a two-year, 3-month solo circumnavigation of the Arctic Circle, and in 2006, along with the Norwegian explorer Børge Ousland, became the first men to travel without a dog or motorised transport to the North Pole during winter, in permanent darkness.

[citation needed] He studied Human Movement Science at the University of Stellenbosch in Western Cape, South Africa.

It was a solitary voyage of two years and three months without motorised transport (boat, kayak, ski kite and on foot) on a 20,000 kilometres (12,000 mi) odyssey.

In a world first, Mike set off on a 60-day voyage on skis without dogs or motorised transportation during the Arctic night with Norwegian explorer Børge Ousland in 2006.

This program consisted of recruiting and then inviting young adults between the ages of 15 and 20 years old, from all over the world – to explore the Earth's continents and travel across the planet's oceans with the PANGAEA expedition-sailing vessel.

Leaving from Switzerland, Horn drove through 13 countries, reaching Pakistan where he attempted to summit K2 (8611 m) in the Karakoram mountain range.

Equipped with his exploration sailing vessel, Pangaea, Mike circumnavigated the globe from Africa to Antarctica, Oceania, Asia, the Arctic, and back to Europe.

The Pole2Pole expedition ended in December 2019 following the completion of Mike's Arctic crossing which brought him back to Europe, his starting point over three years after leaving the Yacht Club of Monaco in May 2016.

On 7 December 2019, just before midnight, Mike Horn and Børge Ousland completed the first ever full crossing of the Arctic Ocean via the North Pole.

The pair left from Nome, Alaska on 28 August 2019, on Mike Horn's exploration sailing vessel Pangaea captained by famous Swiss sailor Bernard Stamm and a small crew.

The two explorers disembarked Pangaea and began their trek across the frozen Arctic Ocean on 12 September 2019, pulling two sledges each weighing over 180 kg.

The main difficulties faced during this adventure were the fragility of the ice due to the seasonal climate and strong negative drifts pushing the duo away from their goal.

The initial plan was to be picked up by Mike's boat Pangaea on the Norwegian side, where the solid ice broke into the open water.

In 2014, Mike and Fred Roux summited the majestic peak of Makalu (8,463 m) in alpine style, without high altitude porters or the use of additional oxygen.

Leaving from Switzerland, Horn drove through 13 countries at the wheels of two Mercedes-Benz G-Class SUVs to finally reach Pakistan where he attempted to summit K2 (8611 m) in the Karakoram mountain range.

Accompanied by his climbing partners, Fred Roux and Köbi Reichen, the team unfortunately did not reach the summit due to unfavourable weather.

Between 2016 and 2018, Horn participated in M6's French version of the American television show: Running Wild with Bear Grylls, named: À L'État Sauvage.

The following six French celebrities embarked on an adventure with Horn: Michael Youn, Matt Pokora, Laure Manaudou, Christophe Dechavanne, Shy'm and Adriana Karembeu.

So far, two episodes of this new show have aired in 2018, featuring celebrities Arnaud Ducret and Bernard de La Villardière, whom he embarked on adventures with in the Philippines.