Jefferies founded the media and publishing group Mondiale in 1991 which he sold to the Daily Mail in 1999 after winning the Queen's Award for Enterprise in 1998.

The story of a young illegal immigrant, rising from poverty to become one of the world's greatest players was released by Disney and has been shown in 38 countries worldwide.

In September 2004 Jefferies, together with Stuart Ford, fronted a bid backed by the Kraft family, to purchase Liverpool Football Club.

In October 2010, as part of a fans' campaign against the ownership, Jefferies conceived and directed a short film entitled 'Dear Mr Hicks' which was released virally via YouTube.

The Independent newspaper praised the video saying: "True to the city's capacity to create something out of adversity, a wonderfully inventive viral film, Dear Mr Hicks, has been published online to make it clear where he ought to go.