[1] Starting his career as an assistant director to Dharmesh Darshan for Lootere in 1993, Luthria made his directorial debut in 1999 with the successful action thriller film Kachche Dhaage.

The film, starring Bollywood veterans Amitabh Bachchan, Akshaye Khanna and Sanjay Dutt, is set during the Indo-Pakistani War of 1971.

It features Bachchan, a major who is captured by the Pakistani army, along with over 30 soldiers during the war and only freed 33 years later by his son, who he has not seen since he was a child, on a rescue mission.

[12] In 2007, Luthria directed the cricket comedy Hattrick, featuring Paresh Rawal, Rimi Sen, Kunal Kapoor, Nana Patekar and Danny Denzongpa.

The film again starred Ajay Devgan, but this time he played a character called Sultan Mirza who is Messiah of the poor, fear of the rich and authority of the powerful, the one whom people turned to when there was nowhere else to look.

[13] In 2011, Milan directed the movie The Dirty Picture starring Vidya Balan, Naseeruddin Shah, Tusshar Kapoor and Emraan Hashmi.

The film is based on the real-life story of the late Southern siren Silk Smitha, who Milan says he even briefly interacted with during her time in the 80s and 90s.