The Grey Towers National Historic Site, the ancestral home of Gifford Pinchot, noted conservationist, two-time governor of Pennsylvania, and first head of the U.S. Forest Service, is located in Milford.

From 1904 to 1926, Grey Towers was the site of summer field study sessions for the Master's degree program of the Yale School of Forestry, together with the Forester's Hall, a commercial building that was adapted and expanded for this purpose.

Nearby is Arisbe, the home of Charles S. Peirce, a prominent logician, philosopher and scientist in the late 19th century, and another NRHP property.

It was kept by stage manager Thomas Gourlay, who passed it down to his daughter, Jeannie, an actress who had appeared in the play, Our American Cousin, at the theatre that night and who later moved to Milford.

[10] In September 2007, Arthur Frommer's Budget Travel named Milford second on its list of "Ten Coolest Small Towns" in Pennsylvania.

Milford is located on the Upper Delaware River, which divides Pennsylvania's Poconos region from the Catskill Mountains in New York, in what was historically a heavily-forested area.

When Judge Biddis bought up the land of what was then known as Wells Ferry[4] and laid out the lots for the new town, he generally followed the urban plan of Philadelphia.

All waterways there which drain into the river fall the 100-foot (30 m) difference in height, creating what is known as a "fluviarchy," a network of waterfalls that is putatively the most notable east of the Rocky Mountains.

Delaware Valley High School serves children from Milford, Matamoras, Shohola, and Dingman areas.

[17] Milford's Hotel Fauchère has hosted multiple prominent guests since 1852, including U.S. presidents Theodore and Franklin Delano Roosevelt and John F. Kennedy, philanthropist Andrew Carnegie, poets Robert Frost and Ogden Nash, baseball's Babe Ruth, and actors Sarah Bernhardt, Charlie Chaplin, Mary Pickford, Rudolph Valentino, and Mae West.

Games played at these tournaments are submitted for rating by the United States Chess Federation (USCF), with which the club is affiliated.

In recent years, stars participating in the film festival have included Farley Granger, Tab Hunter, Marge Champion, Lorna Luft, Arlene Dahl, Larry Kramer and others.

Asante, Alan Alda, Billy Goldstein, Brooke Warner, Suzanne Braun Levine, Anne-Christine d'Adesky, Sean Strub, Mary Badham, Robert Moor, Susan Faludi, Julie Barton, Carol Jenkins, Lucian Truscott IV, Frances FitzGerald, Judge Andrew Napolitano, Phil Klay, John Leland, Ducan Hannah, Bob Eckstein, and others.

Other events include the Festival of Wood, DanceFest Milford, Pike Opera, and "Artwalks" scheduled throughout the year.