[2] Early in the 20th century, Wellsboro was the shipping point and trade center for a large area.

It had fruit evaporators, flour and woolen mills, a milk-condensing plant, marble works, saw mills, foundry and machine shops, and manufactories of cut glass, chemicals, rugs, bolts, cigars, carriages, and furniture.

It is a local tourist destination known for its iconic gas lamps that are spaced through the grass median of Main Street.

Wellsboro was settled in 1806 and incorporated in 1830 and was named in honor of Mary Wells, wife of one of the original settlers, Benjamin Wistar Morris.

[4] The town was the home of George W. Sears (1821–1890), a sportswriter for Field & Stream magazine in the 1880s and an early environmentalist.

Wellsboro was also the site of one of the first factories where light bulbs were mass-produced, using machines whose design remains essentially unchanged from the early 20th century when the Corning company established the plant in the town.

Wellsboro has a humid continental climate (Dfa) with warm to hot summers and cold winters.

Winter generally lasts from December through March, although snow has been recorded in every month except July and August.