Millersburg is a village in Presque Isle County of the U.S. state of Michigan.

According to the United States Census Bureau, the village has a total area of 0.99 square miles (2.56 km2), all land.

The racial makeup of the village was 97.1% White, 1.0% Native American, and 1.9% from two or more races.

34.9% of all households were made up of individuals, and 22.1% had someone living alone who was 65 years of age or older.

21.3% of all households were made up of individuals, and 11.7% had someone living alone who was 65 years of age or older.

About 18.1% of families and 19.8% of the population were below the poverty line, including 28.0% of those under the age of eighteen and 7.9% of those 65 or over.