She is known for her roles as Cindy Williams on the BBC soap opera EastEnders (2013–2015), Ruby Matthews on the Netflix comedy-drama series Sex Education (2019–2023), and Nathalie in the film After Everything (2023).

Keene was born Mimi Roshan Saeed in the Redbridge area of London on 5 August 1998, the daughter of English mother Alexis Keene and British Pakistani father Hassan Saeed.

[2][3] Keene began her career as a child actress on stage, making her professional debut playing Janey in Kin at The Royal Court Theatre from 19 November to 23 December 2010.

[4][5][6] In 2013, she appeared in CBBC's Sadie J as Brandy May Lou and in Our Girl as Jade Dawes.

In 2016, she appeared in an episode of Casualty as Lana Westmore,[8] and played Megan in a short film, The Escape, in 2017.