[3] Besides the local trains on the Mugi Line, some trains of the Muroto limited express service between Mugi and Tokushima and the Home Express Anan from Tokushima to Anan stop at the station.

The station building houses a waiting room and a JR ticket window (without a Midori no Madoguchi facility).

[2][3][6] Minami-Komatsushima Station was opened on 15 December 1916 as an intermediate station along a stretch of track laid down by the privately run Anan Railway (阿南鉄道, Anan Tetsudo) from Chūden to Hanoura and Furushō (now closed).

On 1 April 1987, with the privatization of Japanese National Railways (JNR), the successor of JGR, JR Shikoku took over control of the station.

[7][8] On 1 February 2012, Komatsushima City set up a tourist information centre on the premises of the station.