Minami-ku (南区, Minami-ku) is one of three wards of Sagamihara, Kanagawa, Japan, located in the east part of the city.

The west of Minami-ku faces Chūō-ku.

Minami-ku was created on April 1, 2010, when Sagamihara became a city designated by government ordinance (a "designated city").

As of March 2010, Minami-ku had a population of 272,794, with a land area of 38.2 square kilometers.

This Kanagawa Prefecture location article is a stub.