Mindjammer is set in the distant future, when humans have spread across the universe, and in some cases have evolved into Hominids, races with new abilities.

[1] Humans have also raised various animals to sentience (Xenomorphs), have created androids (Synthetics) to use as cheap labor, as well as sentient spaceships.

[1] In 2008, Cubicle 7 Entertainment published a space opera RPG, Starblazer Adventures that used the FATE System.

In November 2015, Mindjammer Press ran a successful Kickstarter campaign that funded a massive expansion of the line.

"[11] In a review of Mindjammer in Black Gate, Howard Andrew Jones said "lest you think that it’s somehow bereft of fun because it is a little more plausible, rest assured that it oozes adventure.