Mineral Wells is an unincorporated community located in central DeSoto County, Mississippi, United States, near the Mississippi/Tennessee border, just south of Memphis and approximately 3 miles (4.8 km) north of Olive Branch on Mississippi Highway 178.

Mineral Wells is located on the former St. Louis–San Francisco Railway.

[2] A post office operated under the name Mineral Wells from 1910 to 1994.

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