Although one of the last school districts to formulate in New York, Minisink boasts one of the largest campuses in the state, with its buildings, sports fields, and facilities covering 145 acres (0.59 km2) in the western Hudson Valley.
The enrollment of the five schools comprises approximately 4,700 students from the surrounding towns and hamlets of Minisink, Greenville, Wawayanda, New Hampton, Mount Hope, Mamakating and Wallkill.
Minisink Valley's school district includes a voter elected and unpaid Board of Education that has duties regarding legal matters as well as policy review and implementation.
The Mary P. Bonen Otisville Elementary School consists of approximately 400 students with 16 classes in grades K-5.
A new building has been erected in Otisville to meet the growing class sizes, which can be partially explained by the population increase of the region due to suburbanization.