This is a list of the men who have served in the capacity of Minister-President or equivalent office in the states within the region of Mecklenburg from the 18th century to 1952.
In 1990, with German reunification, the state was re-established as Mecklenburg-Vorpommern.
The former districts Rostock, Schwerin, Neubrandenburg and the northern part of Potsdam were merged into the new federal state of Mecklenburg-Vorpommern and the borders was redrawn.
The current and first female Minister-President is Manuela Schwesig, since 2021 heading a coalition government between the Social Democrats and The Left.
The office of the Minister-President is known as the State Chancellery (German: Staatskanzlei), and is located in the capital of Schwerin, along with the rest of the cabinet departments.