The ministry was dissolved on December 10, 2023 following a presidential decree from President Javier Milei.

Decree 141 signed by president Nestor Kirchner in 2003 modifies the Law of Ministries to clearly state the function and objectives of the Ministry of Social development,[10] among which we can name: The Ministry of Social Development has offices in over 50 locations[11] across the country, but the central office is located in what is known as the Ministry of Public Works building, a rationalist style building located in the famous 9 de julio avenue in downtown Buenos Aires, between Moreno street and Belgrano avenue.

After the split during the De la Rúa presidency, of the 22 floors of the building, the top 10 floors house the central offices of Social Development and the bottom 11 to the current Ministry of Health.

By 1947, bulldozing and construction of the avenue reached the southern tip by Moreno street, but the building was spared from demolition, as it was the Ortiz Basualdo palace (headquarters of the French Embassy in Argentina) and the Palacio Álzaga Unzué in the northern end of the avenue.

[12] The building is notable for having two gigantic metal contour portraits of Eva Perón in the south and north facades, as a reminder of her dedication to the social development and welfare of the socially vulnerable population.