Highway 114 serves as a north–south route in west-central Minnesota between Starbuck, Lowry, and La Grand Township near Alexandria.

The route runs concurrent briefly with State Highway 55 on the northern edge of Lowry.

A roundabout is scheduled to be built at State Highway 27 in 2025; currently the intersection is an all way stop.

[1] The highway originally served the city of Garfield, per its legal definition.

When U.S. 52 was replaced by I-94, Highway 114 was truncated to end at the interstate.