Minnesota State Highway 169 (MN 169) is a 48.853-mile-long (78.621 km) highway in northeast Minnesota, which runs from its interchange with U.S. Highway 53 in Wuori Township (immediately north of the city of Virginia) and continues northeast to its northern terminus at the intersection of Lake County Road 18 and Power Dam Road in Fall Lake Township (6-miles east of Ely).

State Highway 169 becomes Lake County Road 18 at this point.

The route runs concurrent with State Highway 1 for 26 miles (42 km) from Vermilion Lake Township (west of Tower) to Ely.

State Highway 169 serves as a north–south route in northeast Minnesota between the cities of Virginia, Tower, Ely, and Winton.

[3] Bear Head Lake State Park is located 7 miles south of the junction of State Highway 169 and County Road 128 (in Eagles Nest Township, 9 miles east of Tower).