When the Fourth Dalai Lama Yonten Gyatso traveled from Mongolia to Tibet in 1601, he was met by an envoy of Mipham Wanggyur Gyalpo, a member of another branch of the family than that of the old gongma.
It appears that he did not renew the bonds with the religious leaders of the Karmapa and Shamarpa, but sought friendly relations with Gelugpa (the school of Dalai Lama) and Drukpa.
[3] The chronicle of the Fifth Dalai Lama, The Song of the Spring Queen, says that "after the zhabdrung gongma [Ngawang Drakpa Gyaltsen] demonstrated how to remove [oneself] to another sphere [i.e., died], the writ of the Phagmodrupa no longer ran.
"[4] The political situation of Central Tibet was disturbed by increasing activity by the Tsangpa ruler Karma Tensung who led a military expedition to Phanyul in 1605.
In 1610 the Tsangpa attacked and completely crushed the important Yargyab polity and moved to restrict the influence of the Gelugpa and their leader, the Third Dalai Lama Yonten Gyatso.