The miR-29 microRNA precursor, or pre-miRNA, is a small RNA molecule in the shape of a stem-loop or hairpin.

Each arm of the hairpin can be processed into one member of a closely related family of short non-coding RNAs that are involved in regulating gene expression.

Many mammalian genomes encode four closely related miR-29 precursors that are transcribed in two transcriptional units.

[2] The mature products are thought to exert regulatory roles by binding with partial complementarity to microRNA recognition elements (MREs) in the 3' untranslated region (3' UTR) of target transcripts.

Experimental evidence suggests that putative targets of mature miR-29 products include the following: