Mir Yusif received his primary education at the Russian-Tatar and city gymnasiums in Irevan.

[2][3] After Armenia fell under Bolshevik influence, he worked at the Military Tribunal of the Armenian Revolutionary Committee and the People's Commissariat of Finance.

He also worked as a research scholar at the History Institute of the Armenian Academy of Sciences and the State Museum.

[7][8] Mir Yusif Mirbabayev played a significant role in the preparation of the Soviet Azerbaijan Encyclopedia.

He authored many articles on linguistics, drawing from sources in Arabic, Persian, Russian, English, French, Ottoman Turkish, and Armenian languages.