[5] Common side effects include high blood pressure, headaches, and urinary tract infections.
[5] Other significant side effects include urinary retention, irregular heart rate, and angioedema.
[7] Mirabegron is also indicated to treat neurogenic detrusor overactivity (NDO), a bladder dysfunction related to neurological impairment, in children ages three years and older.
Beta-3 adrenergic agonists activate brown adipose tissue (BAT) and increase energy expenditure, leading to research interest in their development as weight loss drugs.
[14] A combination of mirabegron and metformin was studied in mice and caused greater weight loss than either drug alone.