Evelia barely has time to give a kiss and hug her father in gratitude for the present when she dies, suddenly, for no apparent reason.

The bishop questions Margarito regarding the girl's religious background and the priest mentions that the toy monkey began to work unexpectedly at the funeral.

The secretary of the ambassador arranges for Margarito to live as the roommate of Antonio, a fellow Colombian and opera singer who is pursuing a career as a soloist tenor.

Margarito does not have much success, as he faces the well intentioned, but bureaucratic Vatican curia, who recommends the embassy route to promote the launching of the beatification process.

Antonio attributes this event to Margarito, who he considers the true saint, admiring his friend's devotion for his daughter, his dignified attitude and his tenacity.

Besieged by the secretary of the Colombian embassy and the Italian mortuary authorities, who want to have the body buried, Margarito pleads with his daughter to wake up.

Milagro en Roma was conceived as one of a series of six films born out of Colombian novelist Gabriel García Márquez's interest in Cinema.

[2] Milagro en Roma was directed by Lisandro Duque and produced by Spanish TV SA and International Network Group under the auspices of the Foundation of New Latin American Cinema as the other films of the Amores Dificiles series.

The story of Milagro en Roma was inspired by a newspaper article published by the author in 1981 entitled The long and happy life of Margarito Duarte which recounts a more than twenty years fruitless battle of a humble Colombian man to have his daughter canonized at the Vatican.