In 1934 Youth Aliyah helped the Jewish children's home, including Miriam, emigrated to Haifa, then part of Palestine.

She created signs for the British Army in Hebrew, Polish, Arabic, Greek, Urdu, French, and English using her graphic expertise.

After her move to America, Laufer used her artistic training to work in various commercial art field including illustration, graphic design, and calligraphy.

[10] From 1961 to 1963 she worked as a teaching assistant for the artists Samuel Adler and Leo Manso in the New York University art department.

[14] The Provincetown Art Association and Museum held a solo retrospective exhibition, Views and Vignettes, the Works of Miriam Laufer, in 2016.

The unabashed and even flamboyant nudes, self-portraits, and luscious landscapes, as well as the critically engaged collage and pop works, with their stenciled statements, seem fresh and relevant today.

Her engagement with autobiographical subject matter and frank depiction of the female body are unusual for a woman painter of her generation."