[1][2] A former senior fellow at the Brookings Institution, Sapiro served as well in the State Department and on the National Security Council under Presidents Reagan, Bush[which?]

She was the founder and president of Summit Strategies International, a consulting firm involved in internet and telecommunications policies.

[9] Sapiro worked in the White House for then-President Bill Clinton as Special Assistant and Counselor to the President for Southeast European Stabilization and Reconstruction.

She also served as Director of European Affairs at the National Security Council, and as a member of the Secretary of State's Policy Planning Staff and Office of Legal Advisers.

[1] Sapiro is a Democrat and was a member of the National Finance Committee of the 2016 Hillary Clinton campaign of the United States presidency.