Miroslava died by suicide in March 1955 by overdosing on sleeping pills, her body found lying outstretched over her bed.

[4] Others, such as actress Katy Jurado, claimed that the picture that Miroslava had between her hands was of Mexican comedian Cantinflas and that her unrequited love was for Cantinflas, but her artistic manager Fanny Schatz exchanged the photo for that of the Dominguín.

[7] Despite a lack of evidence to support it, a rumor persisted that she actually died in a plane crash when traveling with Mexican businessman Jorge Pasquel, and her body was moved to her bedroom and made to look like a suicide.

[8] In his 1983 autobiography, Mon dernier soupir (My Last Breath), Buñuel called Miroslava's cremation following her suicide ironic, as in a scene in Ensayo de un crimen, her last film, the protagonist cremates a wax reproduction of her character.

Her life is the subject of a short story by Guadalupe Loaeza,[9] which was adapted by Alejandro Pelayo for his 1992 Mexican film called Miroslava, starring Arielle Dombasle.