[citation needed] The cerebral cortex and motor homunculus are affected by this, causing the person to be able to read and write backwards quite naturally.
In an experiment conducted by the Department of Neurosurgery at Hokkaido University School of Medicine in Sapporo, Japan, scientists proposed that the origin of mirror writing comes from damage caused through brain trauma or neurological diseases, such as an essential tremor, Parkinson's disease,[4] or spino-cerebellar degeneration.
This hypothesis was proposed because these conditions affect a "neural mechanism that controls the higher cerebral function of writing via the thalamus.
[citation needed] Matteo Zaccolini may have written his original four volume treatise on optics, color, and perspective in the early 17th century in mirror script.
[6] The origins of this mirror writing tradition may date to the pre-Islamic period in rock inscriptions of the western Arabian peninsula.