[3] Louwerse was born in Brisbane, Australia to Dutch parents and attended Ormiston College.

[4] She graduated in December 2006 from the Queensland Conservatorium in Brisbane obtaining a Bachelor of Music in Performance in Classical Voice.

[5] In 2006, Louwerse became the youngest ever winner of the Dame Joan Sutherland Opera Award[6] and went on to record a debut EP entitled She Walks in Beauty.

He listened to her voice on her website and phoned her straight away and two days later she was standing before him in his studio ready to sing.

[13] In this same year, to celebrate Benjamin Britten's 100th birthday, she performed under the baton of John Curro with the Queensland Youth Symphony Britten's War Requiem in the Queensland Performing Arts Centre.

In 2018 Mirusia performed a special concert tour in the Netherlands entitled "An Enchanted Evening" to full houses and exceptional reviews.

[22] Together with the original Seekers (Athol Guy, Keith Potger, Bruce Woodley) Mirusia performed sold-out shows at Brisbane's QPAC Concert Hall, Sydney Recital Hall and Melbourne Recital Centre late 2019.

[30] Mirusia's production company 'Mirusia Productions' won the Redland Business Excellence Award in Creative Industries in October 2022[31] and in November 2022 Mirusia won the Hollywood Music in Media Award for Best Holiday Song with "Snowflake".

She raised more than $260,000 in 2013, for the ACMF, Redland Foundation and Mater Children's Hospital, and was recognised with a 'QLD Volunteer of the Year' Award.

[37] In 2021, Mirusia became the Prima Ambassador for Silver Memories,[38] a program backed by research and clinical studies to help elderly Australians feel socially-engaged and connected through nostalgic music.

In 2024, Mirusia was announced as Redland's Coast Citizen of the Year at the Australia Day Awards for her extensive volunteer work and contributions to music.