Mirza Kamal al-Din Shah Hossein Isfahani (Persian: میرزا کمال الدین شاه حسین اصفهانی), better simply known as Mirza Shah Hossein (میرزا شاه حسین), was an Iranian[1] nobleman, who served as the vakil (vicegerent) and vizier of the Safavid Empire.
Mirza Shah was appointed as vakil and vizier in 1514 after the Battle of Chaldiran, which had a damaging impact on the health of Safavid king Ismail I, who withdrew from affairs of the state and began heavily drinking.
The appointment of Mirza Shah to the vakil office was because he had after the battle found Ismail's favorite wife who was lost in Azerbaijan.
[5] In 1521, Mirza Shah chose to confront his former master, Durmish Khan Shamlu, managing to send him far away from the Safavid court—to Herat in Khorasan, where he was forced to serve as its governor.
[2] However, Mirza Shah Hossein outsmarted himself in the end, and as a result was in 14 April 1523 murdered at the hands of furious Qizilbash members.