It is situated in the eastern part of the Yokote Basin, on alluvial fans formed by the Maruko River and its tributaries, with abundant spring water.

The area of present-day Misato was part of ancient Dewa Province, dominated by the Satake clan during the Edo period, who ruled Kubota Domain under the Tokugawa shogunate.

The area was organized into six villages within Semboku District, Akita with the establishment of the modern municipalities system on April 1, 1889.

In terms of national politics, the town is part of Akita 3rd district of the lower house of the Diet of Japan.

East Japan Railway Company - Ōu Main Line Media related to Misato, Akita at Wikimedia Commons