Having played briefly with 7 Angels 7 Plagues, former Compromise vocalist, Jesse Zaraska, was approached by Ryan Morgan and Kyle Johnson for a new project which would become Misery Signals.

The EP was dedicated to the memory of Jordan Wodehouse and Daniel Langlois, who were killed by a drunk driver on Interstate 20 near Heflin, Alabama while on tour with their band Compromise in support of 7 Angels 7 Plagues.

The band began auditioning vocalists via Myspace, announcing Karl Schubach as Zaraska's replacement with whom they recorded the album, Mirrors.

After extensive touring in support of Controller in early 2009, members of Misery Signals wanted to pursue other musical directions outside of their band.

[8] Hardcore/punk band Burning Empires consists of members from Misery Signals, Fall Out Boy and 7 Angels 7 Plagues, with vocalist Ryan Morgan, bassist Kyle Johnson, guitarists Stu Ross and Matthew Mixon, and drummer Andy Hurley.

Ross officially left Misery Signals on September 25, 2010, to put his focus on Living with Lions, and was reportedly tired of performing heavy metal.

[10] After an extended period of inactivity with a heavy focus on side projects, Misery Signals made an official statement about the state of the band in November 2010.

"[11] The first new release from Misery Signals after going through this major line up change was a cover of Pink Floyd's song "Us and Them" from the 1973 album The Dark Side of the Moon.

[12] In April 2011, Karl Schubach posted a couple tweets mentioning band practice, writing new material in June, and said "We're focusing on bringing the new guys up to speed at the moment."

So far these new songs feel like a purposeful blend of our most recent, more structured Controller record mixed with the chaos and spontaneity of the earlier Of Malice and the Magnum Heart."

On the "Death to False Metalcore Tour 2019" with Darkest Hour and Unearth, the band played a song titled "Sunlifter"[13] from their Absent Light B-Side vinyl release.