Misia Remix 2000 Little Tokyo is the second remix album of Japanese R&B singer Misia, released on April 19, 2000.

It debuted atop of the weekly Oricon albums chart with 234,190 copies sold.

Misia Remix 2000 Little Tokyo is the second highest-selling remix album of all time in Japan, succeeding TRF's Hyper Mix 4.

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