A staff of flight controllers and other support personnel monitor all aspects of the mission using telemetry, and send commands to the vehicle using ground stations.
The training for these missions usually falls under the responsibility of the flight controllers, typically including extensive rehearsals in the MCC.
NASA's Mission Control Center in Houston also manages the U.S. portions of the International Space Station (ISS).
The Mission Control Center of the Russian Federal Space Agency (Russian: Центр управления полётами), also known by its acronym ЦУП ("TsUP") is located in Korolyov, near the RKK Energia plant.
The Jet Propulsion Laboratory (JPL) in Pasadena, California manages all of NASA's uncrewed spacecraft outside Earth's orbit and several research probes within along with the Deep Space Network from the Space Flight Operations Facility.