The M-Braves' first season began on April 18, 2005 at Trustmark Park with a loss to the Montgomery Biscuits.

[3] The Braves defeated the Montgomery Biscuits, 3–2, in the best-of-five series to win the Double-A South championship.

[4] Shea Langeliers was selected as the league's Top MLB Prospect and Dan Meyer as the Manager of the Year.

[6] In 2022, the Double-A South became known as the Southern League, the name historically used by the regional circuit prior to the 2021 reorganization.

[8][9] On September 13, 2008, the Mississippi Braves beat the Carolina Mudcats, 3–2, in the 10th inning of the decisive Game 5 of the Southern League Championship Series.