The Mississippi Valley State Devilettes basketball team represents Mississippi Valley State University in Itta Bena, Mississippi, in NCAA Division I competition.

The school's team competes in the Southwestern Athletic Conference and plays home games in the Harrison HPER Complex.

[2] The Devilettes have never made the NCAA Tournament, but they did play in the 2012 WNIT, losing 68–61 to Tulane in the First Round.

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