She is the daughter of musicians Ryuichi Sakamoto and Akiko Yano.

In 1990, when Sakamoto was 9 years old, her family immigrated to New York, United States, where she lived until she graduated from high school.

[3] While Sakamoto currently lives in Tokyo, she frequently travels back and forth between Japan and New York City, to visit her mother in Manhattan.

[4] Miu Sakamoto is the voice provider for Yamaha's Vocaloid Mew.

Mew's first single, "Line", debuted in The Vocaloid, an album produced by Yamaha.