The Kryeziu are one of three branches of the Buzëzezë (Bucceseos), a feudal Albanian aristocratic clan, which held the Byzantine title of Sebastos since the 11th century.
The clan’s territories included part of the Zadrima plain, the Pukë highlands, and the port of Shëngjin along with the coast up to Velipojë.
In the 15th century, Pal Ziu (Kryeziu), also known as Paolo Zenta, had the Catholic church constructed in Pukë, owned a castle near the town, and, according to Marin Barleti, was a relative of Lekë Dukagjini.
The Ottoman administration recognized their ancient privileges and nobility of medieval origin, with their only obligation being to guard the Vau-Dejës - Kukës route.
In Prizren they were the leading Catholic family, having the noble title of effendi, and were engaged in trade between the Italian peninsula, Constantinople, and the Balkans.