On November 23, 2009, Armenian president Serzh Sargsyan appointed Mkhitar Mnatsakanyan as the Republic's Labour and Social Affairs Minister.

After graduating from the Yerevan State Medical University, Mnatsakanyan served as a surgeon and inter until 1975 and from that year and until 1977 was a forensic expert at one of the districts of Aparan-Aragats.

[1] On May 12, 2007 Mnatsakanyan was elected as deputy of the National Assembly from the Prosperous Armenia party.

On December 6, 2007 he was elected Chairman of the National Assembly Standing Committee on Protection of Human Rights and Public Affairs.

[3] From November 23, 2009 to June 23, 2010, he also served as Minister of Labor and Social Affairs of Armenia.