The team was founded in 1995 as an expansion franchise, joining the ECHL alongside the Louisville RiverFrogs and the Louisiana IceGators.

The Mysticks owed their name to the prevalence of mystic societies—social organizations responsible for throwing parades and balls during the Carnival season—that existed in Mobile since the early 18th century.

The Mobile Mysticks began play in the ECHL as an expansion franchise for the 1995–96 season under head coach and former NHL player Eddie Johnstone.

During this time, they served as a minor league affiliate for the NHL's Philadelphia Flyers and the AHL's Hershey Bears.

[1] His replacement, Matt Shaw, led Mobile to a fifth-place divisional finish and another first-round loss, again in a three-game sweep by the IceGators.