The museum was founded with the mission of attracting broader and younger audiences, and making art accessible to the public.

[2] Moco Museum in Amsterdam opened in 2016[3] on Museumplein, in the historic Villa Alsberg, a townhouse designed in 1904 by Eduard Cuypers the nephew of Pierre Cuypers, designer of Amsterdam Central Station and the Rijksmuseum.

[4] Moco Museum in El Born, Barcelona is in the historic Palau Cervelló-Giudice, formerly the private residence of the noble Cervelló family until the 18th century.

The building incorporates parts of a previous construction from the 15th century, evidenced by the interior courtyard, arched staircase with columns, capitals, and Renaissance-type mouldings.

[5] Furthermore, Palau Cervelló displays an impressive Gothic facade entryway.